Pharmaceutical Ingredients

NIKKOL TO-10MV

Generic name
Polyoxyethylene Sorbitan Monooleate (20E.O.)
  • Emulsifier
    Polysorbate
  • Dispersant

Hydrophilic, nonionic surfactant manufactured by addition polymerization of ethylene oxide to sorbitan monooleate. It is a high safety and widely used as an emulsifier and dispersant. Since this is a manufacturing only pharmaceutical product, it is only available to customers who have a business license for selling and/or manufacturing pharmaceuticals, or for manufacturing cosmetics. Please contact us for EP and USP standards compliance.

*Chemical-navi® members can browse and request samples of products in all three fields.

  • HLB
    • 15.0

    • *measured value

  • Congealing point(reference)
    -5℃
  • Cloud point(reference)
    92-93℃
  • Pour point(reference)
    ≤0℃
  • Usage

    • Stabilizer

    • Stabilizer

    • Surfactant

    • Plasticizer

    • Lubricant

    • Solubilizer

    • Solvent

    • Base

    • Binder

    • Suspending Agent

    • Suspension

    • Coating Agent

    • Wetting Agent

    • Defoamer/ Anti-foaming Agent

    • Emulsifier

    • Adhesive

    • Thickening Agent

    • Excipient

    • Dispersant

    • Disintegrant

    • Co-disintegrant

    • Dissolving Agent

    • Solubilizer/ Dissolution aids

    • Solvent

    • （Referenced from “Japanese Pharmaceutical Excipients Directory, JPED”）

*HLB is measured by O/W emulsification test.

*IOB is calculated using representative values of fatty acid composition.

*Cloud point of surfactant is measured in 1% aqueous.

Route of Administration（Referenced from “Japanese Pharmaceutical Excipients Directory, JPED”）

  • General Topical 100mg/g

  • Transdermal 30mg/g

  • Rectal, Vaginal, Urethral 260mg

  • External Dental / Intraoral 37mg/g

  • Sublingual

  • Ophthalmic 5mg/g

  • Otolaryngological 2mg/g

  • Other External 31mg/g

  • Oral adm. 300mg

  • Masticatory

  • Other Internal 156.8mg

  • Intravenous inj. 500mg

  • Intramuscular inj. 100.2mg

  • Subcutaneous inj. 50mg

  • Intraarterial inj.

  • Spinal / Intracavitary

  • Intradermal inj. 2mg

  • Dental inj.

  • Local anesthetic inj.

  • Other inj. 8.6mg

  • Inhalants

  • Dissolving agent

  • Dialysis

  • Insecticides

  • Others

*For use in injectables, please contact our sales department.

Specifications

Generic namePolyoxyethylene Sorbitan Monooleate (20E.O.)
JP namePolysorbate 80
Standards

JSQI=The Japanese Standards of Quasi-Drug Ingredients
JP=Japanese Pharmacopoeia
JPE=Japanese Pharmaceutical Excipients
JSFA=Japan's Specifications and Standards for Food Additives
Confidential Spec=Confidential Specification of Quasi-drug ingredients

JP, JP
RSPO
Compliant
Appearance
pale yellow to yellow viscous liquid
CAS RN®
9005-65-6
Tariff code (H.S. Code)
3402.42
  • Although every effort has been made to ensure the accuracy of this document, no warranties are expressed or implied as to its contents. For product specifications and quality, please contact our sales department.
  • Some ingredients are not permitted to be sold in certain countries. Please contact our sales department for details.

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