Oily Ingredient
NIKKOL DID
Diester of adipic acid, a dibasic acid, and isopropanol. It is a light feeling oil with excellent skin penetration. It has high polarity and is effective in dissolving drugs.
Pharmaceutical Ingredients
Monoester of sorbitan and oleic acid derived from plants and is a nonionic surfactant with high safety. It is used as a lipophilic emulsifier for W/O emulsion.
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*measured value
Surfactant
Emulsifier
Dispersant
Solubilizer/ Dissolution aids
(Referenced from “Japanese Pharmaceutical Excipients Directory, JPED”)
*HLB is measured by O/W emulsification test.
*IOB is calculated using representative values of fatty acid composition.
*Cloud point of surfactant is measured in 1% aqueous.
General Topical 25mg/g
Transdermal
Rectal, Vaginal, Urethral
External Dental / Intraoral
Sublingual
Ophthalmic
Otolaryngological
Other External 15.464mg
Oral adm. 132mg
Masticatory
Other Internal
Intravenous inj.
Intramuscular inj.
Subcutaneous inj.
Intraarterial inj.
Spinal / Intracavitary
Intradermal inj.
Dental inj.
Local anesthetic inj.
Other inj.
Inhalants
Dissolving agent
Dialysis
Insecticides
Others
Generic name | Sorbitan Monooleate |
---|---|
JPE name | Sorbitan Monooleate |
JSQI=The Japanese Standards of Quasi-Drug Ingredients
JP=Japanese Pharmacopoeia
JPE=Japanese Pharmaceutical Excipients
JSFA=Japan's Specifications and Standards for Food Additives
Confidential Spec=Confidential Specification of Quasi-drug ingredients