Pharmaceutical Ingredients

NIKKOL TL-10

Generic name
Polyoxyethylene Sorbitan Monococoate (20E.O.)
  • Emulsifier
    Polysorbate
  • Solubilizer

Hydrophilic, nonionic surfactant manufactured by addition polymerization of ethylene oxide to sorbitan monolaurate. It is a high safety and widely used as an emulsifier and solubilizer.

*Chemical-navi® members can browse and request samples of products in all three fields.

  • HLB
    • 17.0

    • *measured value

  • Congealing point(reference)
    -5℃
  • Cloud point(reference)
    92-93℃
  • Usage

    • Stabilizer

    • Stabilizer

    • Surfactant

    • Suspending Agent

    • Suspension

    • Wetting Agent

    • Emulsifier

    • Dispersant

    • Solubilizer/ Dissolution aids

    • （Referenced from “Japanese Pharmaceutical Excipients Directory, JPED”）

*HLB is measured by O/W emulsification test.

*IOB is calculated using representative values of fatty acid composition.

*Cloud point of surfactant is measured in 1% aqueous.

Route of Administration（Referenced from “Japanese Pharmaceutical Excipients Directory, JPED”）

  • General Topical 66mg

  • Transdermal

  • Rectal, Vaginal, Urethral

  • External Dental / Intraoral 0.6mg

  • Sublingual

  • Ophthalmic

  • Otolaryngological

  • Other External

  • Oral adm. 0.76mg

  • Masticatory

  • Other Internal

  • Intravenous inj. 40mg

  • Intramuscular inj. 18mg

  • Subcutaneous inj. 1.5mg

  • Intraarterial inj.

  • Spinal / Intracavitary

  • Intradermal inj.

  • Dental inj.

  • Local anesthetic inj.

  • Other inj. 20μg

  • Inhalants

  • Dissolving agent

  • Dialysis

  • Insecticides

  • Others

*For use in injectables, please contact our sales department.

Specifications

Generic namePolyoxyethylene Sorbitan Monococoate (20E.O.)
JPE namePolysorbate 20
Standards

JSQI=The Japanese Standards of Quasi-Drug Ingredients
JP=Japanese Pharmacopoeia
JPE=Japanese Pharmaceutical Excipients
JSFA=Japan's Specifications and Standards for Food Additives
Confidential Spec=Confidential Specification of Quasi-drug ingredients

JPE
RSPO
Compliant
Appearance
pale yellow to yellow liquid
Package size and type
18kg/can
CAS RN®
9005-64-5
ENCS No.
8-55
Tariff code (H.S. Code)
3402.42
  • Although every effort has been made to ensure the accuracy of this document, no warranties are expressed or implied as to its contents. For product specifications and quality, please contact our sales department.
  • Some ingredients are not permitted to be sold in certain countries. Please contact our sales department for details.

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