Pharmaceutical Ingredients

NIKKOL HCO-60

Generic name
Polyoxyethylene Hydrogenated Castor Oil (60E.O.)
  • Emulsifier
    Polyoxyethylene (hydrogenated) Castor Oil
  • Solubilizer

Hydrophilic, nonionic surfactant with a large molecular weight manufactured by addition polymerization of ethylene oxide to hydrogenated castor oil. It is extremely safe and little skin irritation and hemolysis. It is widely used as a solubilizer and is particularly suitable for low alcohol content systems.

*Chemical-navi® members can browse and request samples of products in all three fields.

  • HLB
    • 14.0

    • *measured value

  • Melting Point(reference)
    30-34℃
  • Cloud point(reference)
    ≥98℃
  • Usage

    • Stabilizer

    • Stabilizer

    • Surfactant

    • Solubilizer

    • Solvent

    • Base

    • Suspending Agent

    • Suspension

    • Coating Agent

    • Emulsifier

    • Excipient

    • Dispersant

    • Disintegrant

    • Dissolving Agent

    • Solubilizer/ Dissolution aids

    • Solvent

    • （Referenced from “Japanese Pharmaceutical Excipients Directory, JPED”）

*HLB is measured by O/W emulsification test.

*IOB is calculated using representative values of fatty acid composition.

*Cloud point of surfactant is measured in 1% aqueous.

Route of Administration（Referenced from “Japanese Pharmaceutical Excipients Directory, JPED”）

  • General Topical 60mg/g

  • Transdermal 20mg/g

  • Rectal, Vaginal, Urethral 40mg

  • External Dental / Intraoral 30mg/g

  • Sublingual 50mg/g

  • Ophthalmic 10mg/g

  • Otolaryngological

  • Other External

  • Oral adm. 1.2g

  • Masticatory

  • Other Internal 0.4g

  • Intravenous inj. 9600mg

  • Intramuscular inj. 500mg

  • Subcutaneous inj. 500mg

  • Intraarterial inj.

  • Spinal / Intracavitary 200mg

  • Intradermal inj.

  • Dental inj.

  • Local anesthetic inj.

  • Other inj. 12g

  • Inhalants

  • Dissolving agent

  • Dialysis

  • Insecticides

  • Others

*For use in injectables, please contact our sales department.

Specifications

Generic namePolyoxyethylene Hydrogenated Castor Oil (60E.O.)
JPE namePolyoxyethylene Hydrogenated Castor Oil 60
Standards

JSQI=The Japanese Standards of Quasi-Drug Ingredients
JP=Japanese Pharmacopoeia
JPE=Japanese Pharmaceutical Excipients
JSFA=Japan's Specifications and Standards for Food Additives
Confidential Spec=Confidential Specification of Quasi-drug ingredients

JPE
RSPO
Palm derivative-free
Appearance
white to pale yellow
Package size and type
18kg/can
CAS RN®
61788-85-0
ENCS No.
8-603
Tariff code (H.S. Code)
3402.42
  • Although every effort has been made to ensure the accuracy of this document, no warranties are expressed or implied as to its contents. For product specifications and quality, please contact our sales department.
  • Some ingredients are not permitted to be sold in certain countries. Please contact our sales department for details.

Brochure Download

Most Searched Products

Oily Ingredient

NIKKOL DID

Diester of adipic acid, a dibasic acid, and isopropanol. It is a light feeling oil with excellent skin penetration. It has high polarity and is effective in dissolving drugs.

Surfactant

NIKKOL PBC-34

Hydrophilic, block-type nonionic surfactant manufactured by addition polymerization of ethylene oxide and propylene oxide to cetanol. It is widely used as a solubilizer. It has excellent salt and temperature resistance.

Oily Ingredient

NIKKOL Triester F-810

Triglyceride of glycerin and capric/capric acid. It is a light feeling oil with excellent oxidation and hydrolysis stability. It has high polarity and is effective in dissolving drugs. Compared to edible fats and oils, it is less oily and has better digestion and absorption in the body.

Surfactant

NIKKOL WAX-230

Nonionic self-emulsifying wax consisting of polyoxyethylene (20) arachidyl ether and stearyl alcohol. By mixing 5-10%, emulsions with lamellar liquid crystal structure similar to intercellular lipids in skin can be prepared. The water retained in the liquid crystal structure enhances water retention capacity of the skin.

Return to
Product Search

Original contents