Pharmaceutical Ingredients

NIKKOL HCO-40

Generic name
Polyoxyethylene Hydrogenated Castor Oil (40E.O.)
  • Emulsifier
    Polyoxyethylene (hydrogenated) Castor Oil
  • Solubilizer

Hydrophilic, nonionic surfactant with a large molecular weight manufactured by addition polymerization of ethylene oxide to hydrogenated castor oil. It is extremely safe and little skin irritation. It is widely used as a solubilizer and is particularly suitable for high alcohol content systems.

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  • HLB
    • 12.5

    • *measured value

  • Melting Point(reference)
    30℃
  • Cloud point(reference)
    ≥98℃
  • Usage

    • Base

    • Coating Agent

    • Emulsifier

    • Dispersant

    • Solubilizer/ Dissolution aids

    • （Referenced from “Japanese Pharmaceutical Excipients Directory, JPED”）

*HLB is measured by O/W emulsification test.

*IOB is calculated using representative values of fatty acid composition.

*Cloud point of surfactant is measured in 1% aqueous.

Route of Administration（Referenced from “Japanese Pharmaceutical Excipients Directory, JPED”）

  • General Topical 15mg/g

  • Transdermal

  • Rectal, Vaginal, Urethral 60mg

  • External Dental / Intraoral 9mg/g

  • Sublingual

  • Ophthalmic

  • Otolaryngological

  • Other External

  • Oral adm. 160μg

  • Masticatory

  • Other Internal

  • Intravenous inj.

  • Intramuscular inj.

  • Subcutaneous inj.

  • Intraarterial inj.

  • Spinal / Intracavitary

  • Intradermal inj.

  • Dental inj.

  • Local anesthetic inj.

  • Other inj.

  • Inhalants

  • Dissolving agent

  • Dialysis

  • Insecticides

  • Others

Specifications

Generic namePolyoxyethylene Hydrogenated Castor Oil (40E.O.)
JPE namePolyoxyethylene Hydrogenated Castor Oil 40
Standards

JSQI=The Japanese Standards of Quasi-Drug Ingredients
JP=Japanese Pharmacopoeia
JPE=Japanese Pharmaceutical Excipients
JSFA=Japan's Specifications and Standards for Food Additives
Confidential Spec=Confidential Specification of Quasi-drug ingredients

JPE
RSPO
Palm derivative-free
Appearance
colorless to pale yellow viscous liquid
Package size and type
18kg/can
CAS RN®
61788-85-0
ENCS No.
8-603
Tariff code (H.S. Code)
3402.42
  • Although every effort has been made to ensure the accuracy of this document, no warranties are expressed or implied as to its contents. For product specifications and quality, please contact our sales department.
  • Some ingredients are not permitted to be sold in certain countries. Please contact our sales department for details.

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